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Insulin Resistance Associated with Changes in Behavior
People with diabetes are more prone to anxiety and depression than people with other chronic diseases that have the same level of management. In everyday life, the vulnerability of patients with diabetes experience anxiety and depression are often questionable.
Related to this, a study conducted Joslin Diabetes Center explains the reason why the diabetes prone to anxiety and depression. Told Ronnald C. Kahn, MD, chairman of the Joslin Diabetes Center’s academic, study what they do is the first study to directly state that brain insulin resistance can change a person’s behavior.
The researchers genetically modified mice, making them resistant to insulin brain. As a result, there is anxiety and depression experienced by the rats. Then, it refers to the mechanism of the neurotransmitter dopamine that is low in the area of the brain associated with the condition.
“We also put pressure stress in mice to analyze drugs that can deal with anxiety and depression,” said Dr. Kahn, quoted by Science Daily, Wednesday (04/03/2015).
When the brains of these mice, the scientists found a change in mitochondrial metabolism. In the amendment, the mitochondria increases the production of two enzymes that can degrade dopamine, the main transmitter in the brain behavior. It says Dr. Kahn, the mice produce a normal amount of dopamine. However, due to changes in their mitochondria, then an increase in dopamine metabolism.
“We think that the need to contribute to these behaviors, and even when we give antidepressants in mice that can slow down the degradation of dopamine, we can fix some of the behavioral changes that occur,” said Dr. Kahn.
In previous studies, rats and humans alike have a relationship between insulin resistance and neurodegenerative conditions, particularly in Alzheimer’s disease. Clinical studies have shown that Alzheimer’s patients showed a decrease in the levels of some proteins insulin. It was shown that insulin resistance plays a role in Alzheimer’s disease.
In addition, previous research has demonstrated that insulin-resistant mice can alter protein known as ‘tau’, it is an early symptom of Alzheimer’s disorder. Preliminary studies have shown that treating Alzheimer’s disease with insulin inhaled insulin will be directly sent to the brain and do not make changes to the cognitive function of the brain.
“It’s obviously too early to talk about it, because we are in the early stages of research, but we have intranasal insulin hypothesis has antidepressant effects in patients with diabetes,” said Dr. Kahn.
Want a Happy Life? Just Inadequate Your Sleep Hours
Money can not buy happiness. In fact it is usually the source of happiness comes from things that are trivial and often overlooked people, for example, just sleeping.
A recent survey of more than 7,000 people in the United States in 2014 found that those who sleep more hours had a higher level of welfare than a lack of sleep.
Where do researchers get to this conclusion? The team of researchers from Gallup and Healthways calculates a score based on the answers kuosioner welfare participants that they are bringing about such things as the purpose of life, social relationships, financial condition, engagement with the community, as well as physical health.
Then by the researchers, the results of this questionnaire compared to the number of hours sleep participants. As a result, people who slept for 8 hours per night had an average score of well-being reached 65.7 of 100 points. While those who slept seven hours had scores of 64.2 and 59.4 for those who sleep only 6 hours.
From the same survey, the researchers also found that 42 percent of Americans sleep less than seven hours a night. Though seven hours is the recommended minimum sleep duration National Sleep Foundation to people aged 18 years and over. Similarly, as quoted by LiveScience, Friday (06/03/2015).
“So far we know the level of well-being is also related to work conditions ,. But at least with the results of this survey, the owner of the company may be considering to give their workers more flexible working hours so that they are not sacrificed hours of sleep,” the researchers hope.
To Lose Weight, This Hormones Have Allegedly Effects As Treadmill
Go to the gym for physical activity may be an option some people to maintain or lose weight. However, there are also people who are lazy or do not even like going to the gym. Well, recently US researchers discovered a hormone that allegedly have the same effect with exercise treadmill.
Mots-c, is a hormone that allows a person to lose weight and regulate the body’s blood sugar levels. Discovery by scientists at the University of Southern California is ready to be tested on humans in the next three years.
According to the researchers, the workings mots-c is to increase insulin sensitivity. By doing so, the body will be more effective to process glucose. This hormone works on stimulation of muscle tissue to ward diet and insulin resistance due to aging.
“This is a great progress in the identification of the treatment of age-related diseases such as diabetes,” said Pinchas Cohen, one of the researchers at the University of Shouthern California, quoted by the Daily Mail, Friday (06/03/2015).
Previously, this research has been conducted experiments on mice. Mots-c hormone injected in mice that had been given a high-fat diet can lead to obesity and insulin resistance. This hormone is also injected in mice with insulin resistance due to age.
Changan Lee, an assistant professor at the USC Davis, said, “These findings highlight the mitochondria and its position as an active regulator of metabolism.”
Mots-c is a hormone that is unique because it is located in the mitochondria, cells that convert food into energy, compared with other hormones are encoded in the DNA core. Currently, mots-c has been licensed to a biotechnology company. Meanwhile, human clinical trials will be conducted in three years.
Mahogany Seeds for Health Benefits and side effects
Mahogany widely used stalks, seeds were proved very useful for health. This is because the rich mahogany seed saponins and flavonoids that support the health of the body. Blood circulation is not smooth due to clogged can be treated by taking mahogany seeds. High levels of bad cholesterol can be lowered by mahogany. Benefits mahogany seeds the other is as a pain reliever, reduces fat deposits in the blood vessels, reducing bleeding, fight free');">free radicals, boost immunity, prevent blood clots, improve liver function, neutralize blood sugar levels, etc. Previous article, about the Black Pepper Benefits for Health and Beauty.
Mahogany Seeds for Health Benefits and side effects
Mahogany is anti-fungal and anti-pyretic (lowers the heat). The bitter fruit is also believed to reduce hypertension, restore appetite, treat fever, and improve immunity. Benefit the most from mahogany seeds are as malaria and diabetes medication. While the side effects of the use of mahogany seeds in excessive doses can lead to the formation of gallstones.
How to Eat Seeds Mahogany
1. You can eat mahogany seeds after peeling the outer skin. Of course if you hold it with bitterness.
2. Pour the powder results from mahogany seeds that have been finely ground into hot water.
3. Various mahogany seed extract is now made. There are packaged in the form of powders, capsules, essential oils, instant powder, etc. Choose according to your tastes.
To make the powder, dry beans and then milled until smooth mahogany.
Mahogany seeds is effective for treating the following diseases
– Lack of appetite
– Hypertension
– Fever
– Eczema / Hives
– Diabetes
– Rheumatism
– Sign Wind
– Fever
Mahogany Seeds Use to treat disease
The recommended dose is half a tablespoon of powdered seeds of mahogany. You can make a mahogany seed powder by grinding.
Natural herb use Mahogany Seeds
1. Increasing appetite
Pour ½ tbsp powdered seeds of mahogany into a third cup of hot water. Then, add 1 tablespoon of honey. We recommend that you drink this concoction in warm 3 times a day.
2. Treating Diabetes
Pour half a tablespoon of powdered seeds of mahogany into a third cup of boiling water. In warm, drink this potion of water half an hour before meals. Drink the potion three times a day.
3. Lowering High Blood Pressure
Pour 8 grams of mahogany seeds in 2 cups boiling water. Wait until cool, then strain. Drink the potion in the morning and afternoon, each 1 cup. You can add honey to reduce the bitter taste.
4. Treat fever or colds:
Pour ½ tbsp mahogany seed powder into ¼ cup hot water. Add 1 tablespoon of honey, then drink in the warm 3 times a day.
5. Overcoming eczema and rheumatism
Pour ½ tbsp powdered mahogany seeds in ½ cup hot water. Add honey to taste, then drink warm as much as 3 times a day.
Mahogany Side Effects The use as a natural remedy
Excessive consumption of mahogany seeds can trigger the formation of cholesterol in the bile that can lead to gallstones. This is related to the presence of saponins and flavonoids in mahogany. So, at most dose is 200 mg per day.
Flavonoids contained in mahogany is effective for lowering hypertension. However, excessive use can cause the effect is not good for the body. So, you must be wise to consume these seeds. According to the herbalist, the appropriate dose in mahogany seed ingestion is one seed per day. This is if the beans are eaten directly as a natural remedy. While in extract form, you can adjust the dose.
Do you know??
Mahogany Seeds powder lowers cholesterol and helps to boost your immune system too!
Mahogany Seeds help to regulate blood sugar, you can make a tea of the seeds and drink that or take some of the powder daily for lowering blood sugar levels.
WHAT IS MAHOGANY SEED??
Mahogany as a roadside. Mahogany properties that can survive in arid soil makes it appropriate tree planted by the roadside. For Indonesian peoples especially Javanese, this plant is not a new plant, because since the Dutch colonial era mahogany and colleagues, Tamarind Tree, has been widely planted as a shade on the side of the road especially along roads built by Dutch Government between Anyer to Panarukan. Since last 20 years, the plant began to be ...
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